Human Health and Disease CBSE Class 12 PYQ Chapter Wise

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Answer first

Human Health and Disease PYQs (previous year questions) for CBSE Class 12: Human Health and Disease (Biology) had 27 questions across the 50 official CBSE Class 12 papers we tagged (2016–2026), and appeared in 10 of them. Asked in 10 of 10 years. The concepts asked in the most papers: Immunity, Human Diseases, Drug Abuse.

Year-wise question count

Asked in 10 of 10 years.

Most-asked concepts

Sorted by the number of papers a concept appeared in.

How to practise Human Health and Disease PYQs

1. Start with the concepts at the top of the table. They have come back the most.
2. Solve one year’s Human Health and Disease questions from the official PDF against the clock, then check the answer listed below.
3. Log every miss as a concept gap, a calculation slip or a misread. Each needs a different fix.
4. Once a concept is clean in two papers, move to the next. Then sit a full paper from the year pages.

Questions by year

Each line gives the question number and paper, type, concept, our one-line summary, with a link to the official PDF.

CBSE Class 122026

• Q.2 (Biology (57/1/1)) · MCQ · Immunity: Item that is not part of the immune system PDF
• Q.17 (Biology (57/1/1)) · Very short answer · Immunity: Define humoral immunity and name two antibody types PDF
• Q.26 (Biology (57/1/1)) · Short answer · Drug Abuse: Source plant of opioids; relation and effects of morphine and heroin PDF
• Q.33 (Biology (57/1/1)) · Long answer · Human Diseases: Deadliest malaria parasite, its sexual stage, damage and prevention PDF

CBSE Class 122025

• Q.5 (Biology (57/1/1)) · MCQ · Immunity: Immune response responsible for graft rejection PDF
• Q.17 (Biology (57/1/1)) · Very short answer · Drug Abuse: How morphine and heroin are related and their effects PDF
• Q.23 (Biology (57/1/1)) · Short answer · Human Diseases: Plasmodium life cycle stages and hosts from a diagram PDF
• Q.31 (Biology (57/1/1)) · Long answer · Immunity: MALT, cytokine barriers, AIDS test and roles of bone marrow and thymus PDF

CBSE Class 122024

• Q.7 (Biology (57/1/1)) · MCQ · Allergy: Condition with marked rise in mast cell activity PDF
• Q.20 (Biology (57/1/1)) · Very short answer · Immunity: What is injected after a snakebite and the kind of immunity given PDF
• Q.25 (Biology (57/1/1)) · Short answer · Human Diseases: Complete a table of diseases, pathogens and symptoms PDF
• Q.33 (Biology (57/1/1)) · Long answer · Cancer: Contact inhibition, proto-oncogenes and cancer diagnosis techniques PDF

CBSE Class 122023

• Q.25 (Biology (57/1/1)) · Short answer · Cancer: Malignant vs benign tumours; most feared property of malignancy PDF
• Q.32 (Biology (57/1/1)) · Long answer · Immunity: Interpret antibody levels after vaccination and reinfection PDF

CBSE Class 122022

• Q.1 (Biology Term 2 (57/1/1)) · Short answer · Human Diseases: Body parts affected by pneumonia and common cold; their pathogens PDF
• Q.4 (Biology Term 2 (57/1/1)) · Short answer · Human Diseases: Importance of female Anopheles in the life of Plasmodium PDF

CBSE Class 122020

• Q.4 (Biology (57/1/1)) · MCQ · Immunity: Main barrier stopping microbes entering the body PDF
• Q.8 (Biology (57/1/1)) · Short answer · Immunity: Why childhood measles lowers chance of catching it later PDF
• Q.10 (Biology (57/1/1)) · Short answer · Allergy: Name and explain sudden sneezing and breathlessness on a field trip PDF

CBSE Class 122019

• Q.8 (Biology (57/1/1)) · Short answer · Immunity: Roles of B- and T-lymphocytes in immune responses PDF

CBSE Class 122018

• Q.2 (Biology (57/1)) · Very short answer · Human Diseases: Two diseases controlled by eradicating Aedes mosquitoes PDF
• Q.3 (Biology (57/1)) · Very short answer · Immunity: How cytokine barriers give innate immunity PDF
• Q.10 (Biology (57/1)) · Short answer · Drug Abuse: Source plant of heroin, how it is obtained and its effects PDF
• Q.14 (Biology (57/1)) · Short answer · Immunity: Whether breastfeeding is best for newborns, with reasons PDF

CBSE Class 122017

• Q.8 (Biology (57/1)) · Short answer · Immunity: One use each of passive immunisation, antihistamine, colostrum, cytokine barrier PDF
• Q.15 (Biology (57/1)) · Short answer · Human Diseases: Disease spread by faecally contaminated food and water: pathogen, symptoms, vector PDF

CBSE Class 122016

• Q.15 (Biology (57/1)) · Short answer · Immunity: Basis of lasting immunity after chickenpox; what interferons do PDF

Other Biology chapters

• Reproduction in Organisms PYQs
• Sexual Reproduction in Flowering Plants PYQs
• Human Reproduction PYQs
• Reproductive Health PYQs
• Principles of Inheritance and Variation PYQs
• Molecular Basis of Inheritance PYQs
• Evolution PYQs
• Strategies for Enhancement in Food Production PYQs
• Microbes in Human Welfare PYQs
• Biotechnology: Principles and Processes PYQs
• Biotechnology and its Applications PYQs
• Organisms and Populations PYQs
• Ecosystem PYQs
• Biodiversity and Conservation PYQs
• Environmental Issues PYQs

FAQ

How many Human Health and Disease questions come in CBSE Class 12?

In the official papers we tagged: 4 in 2026, 4 in 2025, 4 in 2024, 2 in 2023, 2 in 2022, 3 in 2020, 1 in 2019, 4 in 2018, 2 in 2017 and 1 in 2016. That is 27 questions in all, about 10% of Biology.

Which Human Health and Disease topics repeat in CBSE Class 12?

Asked in the most papers: Immunity, Human Diseases, Drug Abuse. The concept table lists every one with its count.

Are these official CBSE Class 12 questions?

Yes. Every question is from an official CBSE Class 12 paper hosted on our year pages. The one-line summaries are ours; open the PDF linked beside each question for the full text.